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Dimerization of inositol monophosphatase Mycobacterium tuberculosis SuhB is not constitutive, but induced by binding of the activator Mg(2+)
BACKGROUND: The cell wall of Mycobacterium tuberculosis contains a wide range of phosphatidyl inositol-based glycolipids that play critical structural roles and, in part, govern pathogen-host interactions. Synthesis of phosphatidyl inositol is dependent on free myo-inositol, generated through dephos...
Autores principales: | Brown, Alistair K, Meng, Guoyu, Ghadbane, Hemza, Scott, David J, Dover, Lynn G, Nigou, Jérôme, Besra, Gurdyal S, Fütterer, Klaus |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2080633/ https://www.ncbi.nlm.nih.gov/pubmed/17725819 http://dx.doi.org/10.1186/1472-6807-7-55 |
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