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Ubiquitous expression of the rtTA2S-M2 inducible system in transgenic mice driven by the human hnRNPA2B1/CBX3 CpG island

BACKGROUND: A sensitive, ubiquitously expressed tetracycline inducible system would be a valuable tool in mouse transgenesis. However, this has been difficult to obtain due to position effects observed at different chromosomal sites of transgene integration, which negatively affect expression in man...

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Detalles Bibliográficos
Autores principales: Katsantoni, Eleni Z, Anghelescu, Nora E, Rottier, Robbert, Moerland, Matthijs, Antoniou, Michael, de Crom, Rini, Grosveld, Frank, Strouboulis, John
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2080639/
https://www.ncbi.nlm.nih.gov/pubmed/17900353
http://dx.doi.org/10.1186/1471-213X-7-108