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Site-1 protease is essential for endochondral bone formation in mice

Site-1 protease (S1P) has an essential function in the conversion of latent, membrane-bound transcription factors to their free, active form. In mammals, abundant expression of S1P in chondrocytes suggests an involvement in chondrocyte function. To determine the requirement of S1P in cartilage and b...

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Detalles Bibliográficos
Autores principales: Patra, Debabrata, Xing, Xiaoyun, Davies, Sherri, Bryan, Jennifer, Franz, Carl, Hunziker, Ernst B., Sandell, Linda J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2080931/
https://www.ncbi.nlm.nih.gov/pubmed/18025304
http://dx.doi.org/10.1083/jcb.200708092