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Site-1 protease is essential for endochondral bone formation in mice
Site-1 protease (S1P) has an essential function in the conversion of latent, membrane-bound transcription factors to their free, active form. In mammals, abundant expression of S1P in chondrocytes suggests an involvement in chondrocyte function. To determine the requirement of S1P in cartilage and b...
Autores principales: | Patra, Debabrata, Xing, Xiaoyun, Davies, Sherri, Bryan, Jennifer, Franz, Carl, Hunziker, Ernst B., Sandell, Linda J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2080931/ https://www.ncbi.nlm.nih.gov/pubmed/18025304 http://dx.doi.org/10.1083/jcb.200708092 |
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