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Primary DNA damage and genetic polymorphisms for CYP1A1, EPHX and GSTM1 in workers at a graphite electrode manufacturing plant

BACKGROUND: The results of a cross-sectional study aimed to evaluate whether genetic polymorphisms (biomarkers of susceptibility) for CYP1A1, EPHX and GSTM1 genes that affect polycyclic aromatic hydrocarbons (PAH) activation and detoxification might influence the extent of primary DNA damage (biomar...

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Detalles Bibliográficos
Autores principales: Moretti, Massimo, Dell'Omo, Marco, Villarini, Milena, Pastorelli, Roberta, Muzi, Giacomo, Airoldi, Luisa, Pasquini, Rossana
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2082035/
https://www.ncbi.nlm.nih.gov/pubmed/17908297
http://dx.doi.org/10.1186/1471-2458-7-270