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Association of antigen processing machinery and HLA class I defects with clinicopathological outcome in cervical carcinoma

HLA class I loss is a significant mechanism of immune evasion by cervical carcinoma, interfering with the development of immunotherapies and cancer vaccines. We report the systematic investigation of HLA class I and antigen processing machinery component expression and association with clinical outc...

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Detalles Bibliográficos
Autores principales: Mehta, Akash M., Jordanova, Ekaterina S., Kenter, Gemma G., Ferrone, Soldano, Fleuren, Gert- Jan
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2082063/
https://www.ncbi.nlm.nih.gov/pubmed/17622526
http://dx.doi.org/10.1007/s00262-007-0362-8