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An Obligatory Role of Mind Bomb-1 in Notch Signaling of Mammalian Development

BACKGROUND: The Notch signaling pathway is an evolutionarily conserved intercellular signaling module essential for cell fate specification that requires endocytosis of Notch ligands. Structurally distinct E3 ubiquitin ligases, Neuralized (Neur) and Mind bomb (Mib), cooperatively regulate the endocy...

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Detalles Bibliográficos
Autores principales: Koo, Bon-Kyoung, Yoon, Mi-Jeong, Yoon, Ki-Jun, Im, Sun-Kyoung, Kim, Yoon-Young, Kim, Cheol-Hee, Suh, Pann-Ghill, Jan, Yuh Nung, Kong, Young-Yun
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2082076/
https://www.ncbi.nlm.nih.gov/pubmed/18043734
http://dx.doi.org/10.1371/journal.pone.0001221