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An Obligatory Role of Mind Bomb-1 in Notch Signaling of Mammalian Development
BACKGROUND: The Notch signaling pathway is an evolutionarily conserved intercellular signaling module essential for cell fate specification that requires endocytosis of Notch ligands. Structurally distinct E3 ubiquitin ligases, Neuralized (Neur) and Mind bomb (Mib), cooperatively regulate the endocy...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2082076/ https://www.ncbi.nlm.nih.gov/pubmed/18043734 http://dx.doi.org/10.1371/journal.pone.0001221 |