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Structure-function analysis of the retinoblastoma tumor suppressor protein – is the whole a sum of its parts?
Biochemical analysis of the retinoblastoma protein's function has received considerable attention since it was cloned just over 20 years ago. During this time pRB has emerged as a key regulator of the cell division cycle and its ability to block proliferation is disrupted in the vast majority o...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2082274/ https://www.ncbi.nlm.nih.gov/pubmed/17854503 http://dx.doi.org/10.1186/1747-1028-2-26 |