A Universal Mechanism Ties Genotype to Phenotype in Trinucleotide Diseases

Trinucleotide hereditary diseases such as Huntington disease and Friedreich ataxia are cureless diseases associated with inheriting an abnormally large number of DNA trinucleotide repeats in a gene. The genes associated with different diseases are unrelated and harbor a trinucleotide repeat in diffe...

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Detalles Bibliográficos
Autores principales: Kaplan, Shai, Itzkovitz, Shalev, Shapiro, Ehud
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2082501/
https://www.ncbi.nlm.nih.gov/pubmed/18039028
http://dx.doi.org/10.1371/journal.pcbi.0030235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2082501/
https://www.ncbi.nlm.nih.gov/pubmed/18039028
http://dx.doi.org/10.1371/journal.pcbi.0030235

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