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An Evolutionary-Network Model Reveals Stratified Interactions in the V3 Loop of the HIV-1 Envelope

The third variable loop (V3) of the human immunodeficiency virus type 1 (HIV-1) envelope is a principal determinant of antibody neutralization and progression to AIDS. Although it is undoubtedly an important target for vaccine research, extensive genetic variation in V3 remains an obstacle to the de...

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Detalles Bibliográficos
Autores principales: Poon, Art F. Y, Lewis, Fraser I, Pond, Sergei L. Kosakovsky, Frost, Simon D. W
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2082504/
https://www.ncbi.nlm.nih.gov/pubmed/18039027
http://dx.doi.org/10.1371/journal.pcbi.0030231