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An Evolutionary-Network Model Reveals Stratified Interactions in the V3 Loop of the HIV-1 Envelope
The third variable loop (V3) of the human immunodeficiency virus type 1 (HIV-1) envelope is a principal determinant of antibody neutralization and progression to AIDS. Although it is undoubtedly an important target for vaccine research, extensive genetic variation in V3 remains an obstacle to the de...
Autores principales: | Poon, Art F. Y, Lewis, Fraser I, Pond, Sergei L. Kosakovsky, Frost, Simon D. W |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2082504/ https://www.ncbi.nlm.nih.gov/pubmed/18039027 http://dx.doi.org/10.1371/journal.pcbi.0030231 |
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