Genetic knockout and pharmacologic inhibition of neuronal nitric oxide synthase attenuate nerve injury-induced mechanical hypersensitivity in mice

Neuronal nitric oxide synthase (nNOS) is a key enzyme for nitric oxide production in neuronal tissues and contributes to the spinal central sensitization in inflammatory pain. However, the role of nNOS in neuropathic pain remains unclear. The present study combined a genetic strategy with a pharmaco...

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Detalles Bibliográficos
Autores principales: Guan, Yun, Yaster, Myron, Raja, Srinivasa N, Tao, Yuan-Xiang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2089056/
https://www.ncbi.nlm.nih.gov/pubmed/17922909
http://dx.doi.org/10.1186/1744-8069-3-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2089056/
https://www.ncbi.nlm.nih.gov/pubmed/17922909
http://dx.doi.org/10.1186/1744-8069-3-29

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