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Analysis of the Neurotoxin Complex Genes in Clostridium botulinum A1-A4 and B1 Strains: BoNT/A3, /Ba4 and /B1 Clusters Are Located within Plasmids

BACKGROUND: Clostridium botulinum and related clostridial species express extremely potent neurotoxins known as botulinum neurotoxins (BoNTs) that cause long-lasting, potentially fatal intoxications in humans and other mammals. The amino acid variation within the BoNT is used to categorize the speci...

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Detalles Bibliográficos
Autores principales: Smith, Theresa J., Hill, Karen K., Foley, Brian T., Detter, John C., Munk, A. Christine, Bruce, David C., Doggett, Norman A., Smith, Leonard A., Marks, James D., Xie, Gary, Brettin, Thomas S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2092393/
https://www.ncbi.nlm.nih.gov/pubmed/18060065
http://dx.doi.org/10.1371/journal.pone.0001271