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Transformation of the output of spinal lamina I neurons after nerve injury and microglia stimulation underlying neuropathic pain

BACKGROUND: Disinhibition of neurons in the superficial spinal dorsal horn, via microglia – neuron signaling leading to disruption of chloride homeostasis, is a potential cellular substrate for neuropathic pain. But, a central unresolved question is whether this disinhibition can transform the activ...

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Detalles Bibliográficos
Autores principales: Keller, A Florence, Beggs, Simon, Salter, Michael W, De Koninck, Yves
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2093929/
https://www.ncbi.nlm.nih.gov/pubmed/17900333
http://dx.doi.org/10.1186/1744-8069-3-27