Cargando…
Transformation of the output of spinal lamina I neurons after nerve injury and microglia stimulation underlying neuropathic pain
BACKGROUND: Disinhibition of neurons in the superficial spinal dorsal horn, via microglia – neuron signaling leading to disruption of chloride homeostasis, is a potential cellular substrate for neuropathic pain. But, a central unresolved question is whether this disinhibition can transform the activ...
Autores principales: | Keller, A Florence, Beggs, Simon, Salter, Michael W, De Koninck, Yves |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2093929/ https://www.ncbi.nlm.nih.gov/pubmed/17900333 http://dx.doi.org/10.1186/1744-8069-3-27 |
Ejemplares similares
-
Reduction of anion reversal potential subverts the inhibitory control of firing rate in spinal lamina I neurons: towards a biophysical basis for neuropathic pain
por: Prescott, Steven A, et al.
Publicado: (2006) -
Microglia-independent peripheral neuropathic pain in male and female mice
por: Tu, YuShan, et al.
Publicado: (2022) -
P2Y12 regulates microglia activation and excitatory synaptic transmission in spinal lamina II neurons during neuropathic pain in rodents
por: Yu, Tingting, et al.
Publicado: (2019) -
Microglia in the spinal cord and neuropathic pain
por: Tsuda, Makoto
Publicado: (2015) -
Transcranial direct current stimulation regulates phenotypic transformation of microglia to relieve neuropathic pain induced by spinal cord injury
por: Tan, Mingliang, et al.
Publicado: (2023)