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Mutation Analysis of BRAF, MEK1 and MEK2 in 15 Ovarian Cancer Cell Lines: Implications for Therapy

BACKGROUND: Among gynecologic cancers, ovarian cancer is the second most common and has the highest death rate. Cancer is a genetic disorder and arises due to the accumulation of somatic mutations in critical genes. An understanding of the genetic basis of ovarian cancer has implications both for ea...

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Detalles Bibliográficos
Autores principales: Estep, Anne L., Palmer, Chana, McCormick, Frank, Rauen, Katherine A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2093994/
https://www.ncbi.nlm.nih.gov/pubmed/18060073
http://dx.doi.org/10.1371/journal.pone.0001279