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A specific role for the C-terminal region of the Poly(A)-binding protein in mRNA decay

mRNA poly(A) tails affect translation, mRNA export and mRNA stability, with translation initiation involving a direct interaction between eIF4G and the poly(A)-binding protein Pab1. The latter factor contains four RNA recognition motifs followed by a C-terminal region composed of a linker and a PABC...

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Detalles Bibliográficos
Autores principales: Simón, Ernesto, Séraphin, Bertrand
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094065/
https://www.ncbi.nlm.nih.gov/pubmed/17766253
http://dx.doi.org/10.1093/nar/gkm452