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Engineering the rRNA decoding site of eukaryotic cytosolic ribosomes in bacteria

Structural and genetic studies on prokaryotic ribosomes have provided important insights into fundamental aspects of protein synthesis and translational control and its interaction with ribosomal drugs. Comparable mechanistic studies in eukaryotes are mainly hampered by the absence of both high-reso...

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Detalles Bibliográficos
Autores principales: Hobbie, Sven N., Kalapala, Sarath K., Akshay, Subramanian, Bruell, Christian, Schmidt, Sebastian, Dabow, Sabine, Vasella, Andrea, Sander, Peter, Böttger, Erik C.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094070/
https://www.ncbi.nlm.nih.gov/pubmed/17766247
http://dx.doi.org/10.1093/nar/gkm658