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The human checkpoint sensor Rad9–Rad1–Hus1 interacts with and stimulates DNA repair enzyme TDG glycosylase

Human (h) DNA repair enzyme thymine DNA glycosylase (hTDG) is a key DNA glycosylase in the base excision repair (BER) pathway that repairs deaminated cytosines and 5-methyl-cytosines. The cell cycle checkpoint protein Rad9–Rad1–Hus1 (the 9-1-1 complex) is the surveillance machinery involved in the p...

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Detalles Bibliográficos
Autores principales: Guan, Xin, Madabushi, Amrita, Chang, Dau-Yin, Fitzgerald, Megan E., Shi, Gouli, Drohat, Alexander C., Lu, A-Lien
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094074/
https://www.ncbi.nlm.nih.gov/pubmed/17855402
http://dx.doi.org/10.1093/nar/gkm678