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A novel method for poly(A) fractionation reveals a large population of mRNAs with a short poly(A) tail in mammalian cells

The length of the poly(A) tail of an mRNA plays an important role in translational efficiency, mRNA stability and mRNA degradation. Regulated polyadenylation and deadenylation of specific mRNAs is involved in oogenesis, embryonic development, spermatogenesis, cell cycle progression and synaptic plas...

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Detalles Bibliográficos
Autores principales: Meijer, Hedda A., Bushell, Martin, Hill, Kirsti, Gant, Timothy W., Willis, Anne E., Jones, Peter, de Moor, Cornelia H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095794/
https://www.ncbi.nlm.nih.gov/pubmed/17933768
http://dx.doi.org/10.1093/nar/gkm830