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A novel method for poly(A) fractionation reveals a large population of mRNAs with a short poly(A) tail in mammalian cells
The length of the poly(A) tail of an mRNA plays an important role in translational efficiency, mRNA stability and mRNA degradation. Regulated polyadenylation and deadenylation of specific mRNAs is involved in oogenesis, embryonic development, spermatogenesis, cell cycle progression and synaptic plas...
Autores principales: | Meijer, Hedda A., Bushell, Martin, Hill, Kirsti, Gant, Timothy W., Willis, Anne E., Jones, Peter, de Moor, Cornelia H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095794/ https://www.ncbi.nlm.nih.gov/pubmed/17933768 http://dx.doi.org/10.1093/nar/gkm830 |
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