Papillomavirus E1 helicase assembly maintains an asymmetric state in the absence of DNA and nucleotide cofactors

Concerted, stochastic and sequential mechanisms of action have been proposed for different hexameric AAA+ molecular motors. Here we report the crystal structure of the E1 helicase from bovine papillomavirus, where asymmetric assembly is for the first time observed in the absence of nucleotide cofact...

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Detalles Bibliográficos
Autores principales: Sanders, Cyril M., Kovalevskiy, Oleg V., Sizov, Dmytro, Lebedev, Andrey A., Isupov, Michail N., Antson, Alfred A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095799/
https://www.ncbi.nlm.nih.gov/pubmed/17881379
http://dx.doi.org/10.1093/nar/gkm705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095799/
https://www.ncbi.nlm.nih.gov/pubmed/17881379
http://dx.doi.org/10.1093/nar/gkm705

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