Termination of DNA synthesis by N(6)-alkylated, not 3′-O-alkylated, photocleavable 2′-deoxyadenosine triphosphates

The Human Genome Project has facilitated the sequencing of many species, yet the current Sanger method is too expensive, labor intensive and time consuming to accomplish medical resequencing of human genomes en masse. Of the ‘next-generation’ technologies, cyclic reversible termination (CRT) is a pr...

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Detalles Bibliográficos
Autores principales: Wu, Weidong, Stupi, Brian P., Litosh, Vladislav A., Mansouri, Dena, Farley, Demetra, Morris, Sidney, Metzker, Sherry, Metzker, Michael L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095803/
https://www.ncbi.nlm.nih.gov/pubmed/17881370
http://dx.doi.org/10.1093/nar/gkm689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095803/
https://www.ncbi.nlm.nih.gov/pubmed/17881370
http://dx.doi.org/10.1093/nar/gkm689

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