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Termination of DNA synthesis by N(6)-alkylated, not 3′-O-alkylated, photocleavable 2′-deoxyadenosine triphosphates
The Human Genome Project has facilitated the sequencing of many species, yet the current Sanger method is too expensive, labor intensive and time consuming to accomplish medical resequencing of human genomes en masse. Of the ‘next-generation’ technologies, cyclic reversible termination (CRT) is a pr...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095803/ https://www.ncbi.nlm.nih.gov/pubmed/17881370 http://dx.doi.org/10.1093/nar/gkm689 |