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Different genetic requirements for repair of replication-born double-strand breaks by sister-chromatid recombination and break-induced replication

Homologous recombination (HR) is the major mechanism used to repair double-strand breaks (DSBs) that result from replication, but a study of repair of DSBs specifically induced during S-phase is lacking. Using an inverted-repeat assay in which a DSB is generated by the encountering of the replicatio...

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Detalles Bibliográficos
Autores principales: Cortés-Ledesma, Felipe, Tous, Cristina, Aguilera, Andrés
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095809/
https://www.ncbi.nlm.nih.gov/pubmed/17905819
http://dx.doi.org/10.1093/nar/gkm488