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Different genetic requirements for repair of replication-born double-strand breaks by sister-chromatid recombination and break-induced replication
Homologous recombination (HR) is the major mechanism used to repair double-strand breaks (DSBs) that result from replication, but a study of repair of DSBs specifically induced during S-phase is lacking. Using an inverted-repeat assay in which a DSB is generated by the encountering of the replicatio...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095809/ https://www.ncbi.nlm.nih.gov/pubmed/17905819 http://dx.doi.org/10.1093/nar/gkm488 |