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Global control of aberrant splice-site activation by auxiliary splicing sequences: evidence for a gradient in exon and intron definition
Auxiliary splicing signals play a major role in the regulation of constitutive and alternative pre-mRNA splicing, but their relative importance in selection of mutation-induced cryptic or de novo splice sites is poorly understood. Here, we show that exonic sequences between authentic and aberrant sp...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095810/ https://www.ncbi.nlm.nih.gov/pubmed/17881373 http://dx.doi.org/10.1093/nar/gkm680 |