Escherichia coli HU protein has a role in the repair of abasic sites in DNA

Mostrar otras versiones (1)

HU is one of the most abundant DNA binding proteins in Escherichia coli. We find that it binds strongly to DNA containing an abasic (AP) site or tetrahydrofuran (THF) (apparent K(d) ≈50 nM). It also possesses an AP lyase activity that cleaves at a deoxyribose but not at a THF residue. The binding an...

Descripción completa

Detalles Bibliográficos
Autores principales: Kow, Yoke W., Imhoff, Barry, Weiss, Bernard, Hung, David C. I., Hindoyan, Antreas A., Story, Randall M., Goodman, Steven D.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095813/
https://www.ncbi.nlm.nih.gov/pubmed/17916578
http://dx.doi.org/10.1093/nar/gkm567

Ejemplares similares

Ejemplares similares