Guanosine stimulates neurite outgrowth in PC12 cells via activation of heme oxygenase and cyclic GMP

Undifferentiated rat pheochromocytoma (PC12) cells extend neurites when cultured in the presence of nerve growth factor (NGF). Extracellular guanosine synergistically enhances NGF-dependent neurite outgrowth. We investigated the mechanism by which guanosine enhances NGF-dependent neurite outgrowth....

Descripción completa

Detalles Bibliográficos
Autores principales: Bau, Christian, Middlemiss, Pamela J., Hindley, Shaun, Jiang, Shucui, Ciccarelli, Renata, Caciagli, Francesco, DiIorio, Patrizia, Werstiuk, Eva S., Rathbone, Michel P.
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2005
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096532/
https://www.ncbi.nlm.nih.gov/pubmed/18404501
http://dx.doi.org/10.1007/s11302-005-6214-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096532/
https://www.ncbi.nlm.nih.gov/pubmed/18404501
http://dx.doi.org/10.1007/s11302-005-6214-0

Ejemplares similares