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P2X(7) nucleotide receptors mediate caspase-8/9/3-dependent apoptosis in rat primary cortical neurons

Apoptosis is a major cause of cell death in the nervous system. It plays a role in embryonic and early postnatal brain development and contributes to the pathology of neurodegenerative diseases. Here, we report that activation of the P2X(7) nucleotide receptor (P2X(7)R) in rat primary cortical neuro...

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Detalles Bibliográficos
Autores principales: Kong, Qiongman, Wang, Min, Liao, Zhongji, Camden, Jean M., Yu, Sue, Simonyi, Agnes, Sun, Grace Y., Gonzalez, Fernando A., Erb, Laurie, Seye, Cheikh I., Weisman, Gary A.
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096553/
https://www.ncbi.nlm.nih.gov/pubmed/18404518
http://dx.doi.org/10.1007/s11302-005-7145-5