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Molecular mechanisms of extracellular adenine nucleotides-mediated inhibition of human Cd4(+) T lymphocytes activation

We have previously reported that ATPγS, a slowly hydrolyzed analog of ATP, inhibits the activation of human CD4(+) T lymphocytes by anti-CD3 and anti-CD28 mAb. In this report we have partially characterized the signaling mechanisms involved in this immunosuppressive effect. ATPγS had no inhibitory e...

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Detalles Bibliográficos
Autores principales: Duhant, Xavier, Suarez Gonzalez, Nathalie, Schandené, Liliane, Goldman, Michel, Communi, Didier, Boeynaems, Jean-Marie
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096556/
https://www.ncbi.nlm.nih.gov/pubmed/18404522
http://dx.doi.org/10.1007/s11302-005-8077-9