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Extracellular zinc and ATP-gated P2X receptor calcium entry channels: New zinc receptors as physiological sensors and therapeutic targets

In this review, we focus on two attributes of P2X receptor channel function, one essential and one novel. First, we propose that P2X receptors are extracellular sensors as well as receptors and ion channels. In particular, the large extracellular domain (that comprises 70% of the molecular mass of t...

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Detalles Bibliográficos
Autores principales: Schwiebert, Erik M., Liang, Lihua, Cheng, Nai-Lin, Williams, Clintoria Richards, Olteanu, Dragos, Welty, Elisabeth A., Zsembery, Akos
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096558/
https://www.ncbi.nlm.nih.gov/pubmed/18404515
http://dx.doi.org/10.1007/s11302-005-0777-7