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Extracellular zinc and ATP-gated P2X receptor calcium entry channels: New zinc receptors as physiological sensors and therapeutic targets
In this review, we focus on two attributes of P2X receptor channel function, one essential and one novel. First, we propose that P2X receptors are extracellular sensors as well as receptors and ion channels. In particular, the large extracellular domain (that comprises 70% of the molecular mass of t...
Autores principales: | Schwiebert, Erik M., Liang, Lihua, Cheng, Nai-Lin, Williams, Clintoria Richards, Olteanu, Dragos, Welty, Elisabeth A., Zsembery, Akos |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096558/ https://www.ncbi.nlm.nih.gov/pubmed/18404515 http://dx.doi.org/10.1007/s11302-005-0777-7 |
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