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Delineation of ligand binding and receptor signaling activities of purified P2Y receptors reconstituted with heterotrimeric G proteins

P2Y receptors are G protein coupled receptors that respond to extracellular nucleotides to promote a multitude of signaling events. Our laboratory has purified several P2Y receptors with the goal of providing molecular insight into their: (1) ligand binding properties, (2) G protein signaling select...

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Detalles Bibliográficos
Autores principales: Bodor, Erik T., Waldo, Gary L., Blaesius, Rainer, Harden, T. Kendall
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096568/
https://www.ncbi.nlm.nih.gov/pubmed/18404399
http://dx.doi.org/10.1007/s11302-004-4748-1