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Concerted Transcriptional Regulation by BRCA1 and COBRA1 in Breast Cancer Cells

Cofactor of BRCA1 (COBRA1) was first identified as a protein that binds to the breast cancer susceptibility gene product BRCA1. COBRA1 modulates estrogen-dependent and independent transcription and suppresses the growth of breast cancer cells. Its expression is significantly reduced in metastatic an...

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Detalles Bibliográficos
Autores principales: Aiyar, Sarah E., Cho, HyungJun, Lee, Jae, Li, Rong
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096739/
https://www.ncbi.nlm.nih.gov/pubmed/18071589