Downregulation of CD94/NKG2A inhibitory receptors on CD8(+ )T cells in HIV infection is more pronounced in subjects with detected viral load than in their aviraemic counterparts

The CD94/NKG2A heterodimer is a natural killer receptor (NKR), which inhibits cell-mediated cytotoxicity upon interaction with MHC class I gene products. It is expressed by NK cells and by a small fraction of activated CD8(+ )T lymphocytes. Abnormal upregulation of the CD94/NKG2A inhibitory NKR on c...

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Detalles Bibliográficos
Autores principales: Zeddou, Mustapha, Rahmouni, Souad, Vandamme, Arnaud, Jacobs, Nathalie, Frippiat, Frédéric, Leonard, Philippe, Schaaf-Lafontaine, Nicole, Vaira, Dolores, Boniver, Jacques, Moutschen, Michel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2098781/
https://www.ncbi.nlm.nih.gov/pubmed/17927817
http://dx.doi.org/10.1186/1742-4690-4-72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2098781/
https://www.ncbi.nlm.nih.gov/pubmed/17927817
http://dx.doi.org/10.1186/1742-4690-4-72

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