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Excess Single-Stranded DNA Inhibits Meiotic Double-Strand Break Repair
During meiosis, self-inflicted DNA double-strand breaks (DSBs) are created by the protein Spo11 and repaired by homologous recombination leading to gene conversions and crossovers. Crossover formation is vital for the segregation of homologous chromosomes during the first meiotic division and requir...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2098809/ https://www.ncbi.nlm.nih.gov/pubmed/18081428 http://dx.doi.org/10.1371/journal.pgen.0030223 |