Excess Single-Stranded DNA Inhibits Meiotic Double-Strand Break Repair

During meiosis, self-inflicted DNA double-strand breaks (DSBs) are created by the protein Spo11 and repaired by homologous recombination leading to gene conversions and crossovers. Crossover formation is vital for the segregation of homologous chromosomes during the first meiotic division and requir...

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Detalles Bibliográficos
Autores principales: Johnson, Rebecca, Borde, Valérie, Neale, Matthew J, Bishop-Bailey, Anna, North, Matthew, Harris, Sheila, Nicolas, Alain, Goldman, Alastair S. H
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2098809/
https://www.ncbi.nlm.nih.gov/pubmed/18081428
http://dx.doi.org/10.1371/journal.pgen.0030223

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