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Chromatin modification of Apaf-1 restricts the apoptotic pathway in mature neurons

Although apoptosis has been extensively studied in developing neurons, the dynamic changes in this pathway after neuronal maturation remain largely unexplored. We show that as neurons mature, cytochrome c– mediated apoptosis progresses from inhibitor of apoptosis protein–dependent to –independent re...

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Detalles Bibliográficos
Autores principales: Wright, Kevin M., Smith, Michelle I., Farrag, Lila, Deshmukh, Mohanish
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099178/
https://www.ncbi.nlm.nih.gov/pubmed/18056406
http://dx.doi.org/10.1083/jcb.200708086