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Chromatin modification of Apaf-1 restricts the apoptotic pathway in mature neurons
Although apoptosis has been extensively studied in developing neurons, the dynamic changes in this pathway after neuronal maturation remain largely unexplored. We show that as neurons mature, cytochrome c– mediated apoptosis progresses from inhibitor of apoptosis protein–dependent to –independent re...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099178/ https://www.ncbi.nlm.nih.gov/pubmed/18056406 http://dx.doi.org/10.1083/jcb.200708086 |