Regulation of Rap1 activity by RapGAP1 controls cell adhesion at the front of chemotaxing cells

Spatial and temporal regulation of Rap1 is required for proper myosin assembly and cell adhesion during cell migration in Dictyostelium discoideum. Here, we identify a Rap1 guanosine triphosphatase–activating protein (GAP; RapGAP1) that helps mediate cell adhesion by negatively regulating Rap1 at th...

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Detalles Bibliográficos
Autores principales: Jeon, Taeck J., Lee, Dai-Jen, Lee, Susan, Weeks, Gerald, Firtel, Richard A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099181/
https://www.ncbi.nlm.nih.gov/pubmed/18039932
http://dx.doi.org/10.1083/jcb.200705068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099181/
https://www.ncbi.nlm.nih.gov/pubmed/18039932
http://dx.doi.org/10.1083/jcb.200705068

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