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A function for tyrosine phosphorylation of type 1 inositol 1,4,5-trisphosphate receptor in lymphocyte activation

Sustained elevation of intracellular calcium by Ca(2+) release–activated Ca(2+) channels is required for lymphocyte activation. Sustained Ca(2+) entry requires endoplasmic reticulum (ER) Ca(2+) depletion and prolonged activation of inositol 1,4,5-trisphosphate receptor (IP(3)R)/Ca(2+) release channe...

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Detalles Bibliográficos
Autores principales: deSouza, Nikhil, Cui, Jie, Dura, Miroslav, McDonald, Thomas V., Marks, Andrew R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099184/
https://www.ncbi.nlm.nih.gov/pubmed/18056410
http://dx.doi.org/10.1083/jcb.200708200