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A function for tyrosine phosphorylation of type 1 inositol 1,4,5-trisphosphate receptor in lymphocyte activation
Sustained elevation of intracellular calcium by Ca(2+) release–activated Ca(2+) channels is required for lymphocyte activation. Sustained Ca(2+) entry requires endoplasmic reticulum (ER) Ca(2+) depletion and prolonged activation of inositol 1,4,5-trisphosphate receptor (IP(3)R)/Ca(2+) release channe...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099184/ https://www.ncbi.nlm.nih.gov/pubmed/18056410 http://dx.doi.org/10.1083/jcb.200708200 |