Endothelin-converting enzyme-1 regulates endosomal sorting of calcitonin receptor-like receptor and β-arrestins

Although cell surface metalloendopeptidases degrade neuropeptides in the extracellular fluid to terminate signaling, the function of peptidases in endosomes is unclear. We report that isoforms of endothelin-converting enzyme-1 (ECE-1a–d) are present in early endosomes, where they degrade neuropeptid...

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Detalles Bibliográficos
Autores principales: Padilla, Benjamin E., Cottrell, Graeme S., Roosterman, Dirk, Pikios, Stella, Muller, Laurent, Steinhoff, Martin, Bunnett, Nigel W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099187/
https://www.ncbi.nlm.nih.gov/pubmed/18039931
http://dx.doi.org/10.1083/jcb.200704053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099187/
https://www.ncbi.nlm.nih.gov/pubmed/18039931
http://dx.doi.org/10.1083/jcb.200704053

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