Site-specific ubiquitination exposes a linear motif to promote interferon-α receptor endocytosis

Ligand-induced endocytosis and lysosomal degradation of cognate receptors regulate the extent of cell signaling. Along with linear endocytic motifs that recruit the adaptin protein complex 2 (AP2)–clathrin molecules, monoubiquitination of receptors has emerged as a major endocytic signal. By investi...

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Detalles Bibliográficos
Autores principales: Kumar, K.G. Suresh, Barriere, Hervé, Carbone, Christopher J., Liu, Jianghuai, Swaminathan, Gayathri, Xu, Ping, Li, Ying, Baker, Darren P., Peng, Junmin, Lukacs, Gergely L., Fuchs, Serge Y.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099190/
https://www.ncbi.nlm.nih.gov/pubmed/18056411
http://dx.doi.org/10.1083/jcb.200706034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099190/
https://www.ncbi.nlm.nih.gov/pubmed/18056411
http://dx.doi.org/10.1083/jcb.200706034

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