Variable expressivity of the tumour suppressor protein TRP53 in cryopreserved human blastocysts

In a mouse model, in vitro fertilization or extended embryo culture leads to the increased expression of TRP53 in susceptible embryos. Ablation of the TRP53 gene improved embryo viability indicating that increased expression of TRP53 is a cause of the reduction of embryo viability resulting from in...

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Detalles Bibliográficos
Autores principales: Chandrakanthan, Vashe, Chami, Omar, Stojanov, Tomas, O'Neill, Chris
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099431/
https://www.ncbi.nlm.nih.gov/pubmed/17939878
http://dx.doi.org/10.1186/1477-7827-5-39

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099431/
https://www.ncbi.nlm.nih.gov/pubmed/17939878
http://dx.doi.org/10.1186/1477-7827-5-39

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