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Variable expressivity of the tumour suppressor protein TRP53 in cryopreserved human blastocysts
In a mouse model, in vitro fertilization or extended embryo culture leads to the increased expression of TRP53 in susceptible embryos. Ablation of the TRP53 gene improved embryo viability indicating that increased expression of TRP53 is a cause of the reduction of embryo viability resulting from in...
Autores principales: | Chandrakanthan, Vashe, Chami, Omar, Stojanov, Tomas, O'Neill, Chris |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099431/ https://www.ncbi.nlm.nih.gov/pubmed/17939878 http://dx.doi.org/10.1186/1477-7827-5-39 |
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