Preliminary nanopore cheminformatics analysis of aptamer-target binding strength

BACKGROUND: Aptamers are nucleic acids selected for their ability to bind to molecules of interest and may provide the basis for a whole new class of medicines. If the aptamer is simply a dsDNA molecule with a ssDNA overhang (a "sticky" end) then the segment of ssDNA that complements that...

Descripción completa

Detalles Bibliográficos
Autores principales: Thomson, Karen, Amin, Iftekhar, Morales, Eric, Winters-Hilt, Stephen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099479/
https://www.ncbi.nlm.nih.gov/pubmed/18047710
http://dx.doi.org/10.1186/1471-2105-8-S7-S11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099479/
https://www.ncbi.nlm.nih.gov/pubmed/18047710
http://dx.doi.org/10.1186/1471-2105-8-S7-S11

Ejemplares similares