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Preliminary nanopore cheminformatics analysis of aptamer-target binding strength
BACKGROUND: Aptamers are nucleic acids selected for their ability to bind to molecules of interest and may provide the basis for a whole new class of medicines. If the aptamer is simply a dsDNA molecule with a ssDNA overhang (a "sticky" end) then the segment of ssDNA that complements that...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099479/ https://www.ncbi.nlm.nih.gov/pubmed/18047710 http://dx.doi.org/10.1186/1471-2105-8-S7-S11 |