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Nanopore-based kinetics analysis of individual antibody-channel and antibody-antigen interactions

BACKGROUND: The UNO/RIC Nanopore Detector provides a new way to study the binding and conformational changes of individual antibodies. Many critical questions regarding antibody function are still unresolved, questions that can be approached in a new way with the nanopore detector. RESULTS: We prese...

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Detalles Bibliográficos
Autores principales: Winters-Hilt, Stephen, Morales, Eric, Amin, Iftekhar, Stoyanov, Alexander
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099489/
https://www.ncbi.nlm.nih.gov/pubmed/18047720
http://dx.doi.org/10.1186/1471-2105-8-S7-S20