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New insight into the role of the β3 subunit of the GABA(A)-R in development, behavior, body weight regulation, and anesthesia revealed by conditional gene knockout

BACKGROUND: The β3 subunit of the γ-aminobutyric acid type A receptor (GABA(A)-R) has been reported to be important for palate formation, anesthetic action, and normal nervous system function. This subunit has also been implicated in the pathogenesis of Angelman syndrome and autism spectrum disorder...

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Detalles Bibliográficos
Autores principales: Ferguson, Carolyn, Hardy, Steven L, Werner, David F, Hileman, Stanley M, DeLorey, Timothy M, Homanics, Gregg E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2100059/
https://www.ncbi.nlm.nih.gov/pubmed/17927825
http://dx.doi.org/10.1186/1471-2202-8-85